Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

In a move akin to puncturing an egg yolk without breaking the shell or egg white, researchers have figured out how to pierce the nucleus of a cell without hurting the rest of the structure. The ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...