Searches were carried out in the Medline, Embase and PubMed databases in July 2014 with a date range, 1960-2013. Observational cohort studies (either prospective or retrospective) were included.

Leukoplakia: A white spot or patch in the mouth. Cancer: A term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and can spread through the ...

Is there a direct relationship between oral leukoplakia and tobacco and alcohol consumption? Do all oral leukoplakias lead to oral squamous cell carcinoma (OSCC)? Is it possible to detect premalignant ...

Sir, leukoplakia is a common lesion observed in clinical practice and the term is familiar to the majority of dentists. But a review of the literature reveals that there is considerable ambiguity in ...