Figure 1: Construction of hexon HVR-chimaeric rAd5 vectors. Figure 2: Cellular immune responses elicited by hexon HVR-chimaeric rAd5 vectors. These studies demonstrate that targeted HVR modification ...
The immunogenicity of adenovirus (Ad) vectors is enhanced by virus-specific memory immune responses present in most individuals as a result of past exposure to these ubiquitous pathogens. We ...
Human adenoviruses typically cause self-limited respiratory, gastrointestinal, and conjunctival infections in healthy children. In late 2021 and early 2022, several previously healthy children were ...