Changes in the ascending cholinergic neurons of the brain might contribute to the symptoms of neurodegenerative disorders. Hirano et al. studied brain acetylcholinesterase (AChE) activity in patients ...

Three the approved drugs for Alzheimer’s disease attempt to boost the brain’s supply of acetylcholine, a critical neurotransmitter for cognition that wanes in people with the disease. But might ...

Efficacy of thalidomide, neurokinin-1 receptor antagonist, and olanzapine in combination with palonosetron plus dexamethasone in preventing chemotherapy-induced nausea and vomiting (CINV) induced by ...

Factors associated with efficacy of TAS-102 in patients with refractory metastatic colorectal cancer (mCRC). This is an ASCO Meeting Abstract from the . This abstract does not include a full text ...

Subtle changes in neurotransmission that occur during Alzheimer’s disease have been tough to track in living people. A new positron emission tomography tracer may change that. In the January 12 ...

A link between anticholinergic drug use and cognitive impairment was recently observed from observational studies on randomized clinical trials. Regenstrief Institute research scientists examined ...